Musculoskeletal cancers in adolescents.

What are the symptoms of musculoskeletal cancers in adolescents? The most common symptom is pain. Often the pain is associated with an incidental episode of trauma. However, trauma is neither related to nor causative of the lesion. Unlike pain due to trauma (eg, fracture, muscle pull), pain due to musculoskeletal tumors does not decrease with time; rather, it increases with time. Night pain and pain at rest are also typical of pain due to a musculoskeletal tumor. As the lesion progresses and enlarges, the pain will become associated with use of the extremity or weight bearing. The development of a mass is also common.